br In conclusion these hypothesis generating findings support further consideration
In conclusion, these hypothesis-generating findings support further consideration of adjuvant regimens that include the delivery of CT be-fore RT. For women with locally advanced Type 1 EC, treatment with multi-agent CT before RT (or potentially employing a sandwich ap-proach) may optimize control of both locoregional and distant disease, ultimately leading to longer PFS and OS. The findings presented here support the consideration of this Cycloheximide regimen in the design of future pro-spective trials.
Supplementary data to this article can be found online at https://doi.
We acknowledge the NCDB for collecting the data used in these anal-yses. The NCDB and the participating hospitals are the source of the data. The NCDB has not verified and are not responsible for the statisti-cal validity of the data analysis or conclusions.
Conflict of interest statement
Dr. Matei reports personal fees from Astra Zeneca, Genentech/Roche, Tesaro, Astex, Clovis, and the European commission that are outside the submitted work. All other authors report no conflicts of interest.
Conceptualization: Goodman, Seagle, Strauss. Formal Analysis and
Methodology: Goodman, Strauss, Hatoum, Seagle. Writing – Original
Draft: Goodman, Hatoum; Writing – Review and Editing: Goodman,
Hatoum, Seagle, Barber, Matei, Strauss. Project Administration: Hatoum,
Donnelly, Barber, Matei, Shahabi, Strauss. Supervision: Strauss, Shahabi.
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