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br Recombinant adenoviruses Ad Apoptin
2020-08-12
Recombinant adenoviruses Ad-Apoptin-hTERTp-E1a (Ad-VT), Ad-hTERTp-E1a (Ad-T), Ad-Apoptin (Ad-vp3), and Ad-mock were constructed and preserved in our labora-tory (Laboratory of molecular Virology and Immunology, Military Medical Science Academy of the PLA, Chang-chun, China) (Fig. 1) [30]. The c
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br Scheme Schematic representation of
2020-08-12
Scheme 1. Schematic representation of antibody-conjugated MNP-Si preparation. (A), Separation of Sk-BR-3 cells from PBMCs with Ab/MNP-Si. (B) Analysis with flow cytometry (C). washed with PBS 1× in a magnetic field (gradient of 0.5 T/m) for 15–20 min. Because the final product (Ab/MNP-Si) has p
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br Subhash VV Tan SH Tan WL
2020-08-12
36. Subhash VV, Tan SH, Tan WL, et al. GTSE1 expression re-presses apoptotic signaling and confers cisplatin resistance in gastric cancer cells. BMC Cancer. 2015;15:550. 37. Chen F, Jin X, Zhao J, Gou S. DN604: a platinum(II) drug candidate with classic SAR can induce apoptosis via suppressing
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br Mobile phone use was estimated from the national
2020-08-12
Mobile phone use was estimated from the national number of cel-lular mobile phone subscriptions obtained and was obtained from the United Nations specialized agency for information and communication technologies (ITU, 2016). data were obtained after a Data Access Agreement with ONS was put in p
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br Corresponding author br closely associated with the progn
2020-08-12
Corresponding author. closely associated with the prognosis of patients with advanced GC [8–10]. Therefore, identification of the phenotype of GC differentiation will facilitate the implementation of effective chemotherapy regimens and accurate predict patient outcomes. Currently, pathologists
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Tauroursodeoxycholate Pinquart M Duberstein PR Information n
2020-08-12
[11] Pinquart M, Duberstein PR. Information needs and decision-making processes in older cancer patients. Crit Rev Oncol Hematol 2004;51(1):69–80. [12] Bluethmann SM, Mariotto AB, Rowland JH. Anticipating the “silver tsunami”: preva-lence trajectories and comorbidity burden among older Cancer survi
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br antiproliferative effects against PC cancer cells In addi
2020-08-10
antiproliferative effects against PC-3 cancer cells. In addition to its in-duction of HSP90 expression, 11 also downregulates the protein ex-pression levels of client proteins, such as EGFR, Src, FAK, and RB. The significant inhibition of the HSP90 chaperone by 11 was rationalized by its molecular
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br Preparation of CuO NPs br About mL
2020-08-07
2.2. Preparation of CuO NPs About 50 mL of fresh Coleus aromaticus leaf extract was added to 10 mL of 0.01 M CuSO4 aqueous solution and mixed well by manual shaking. The reaction mixture was then heated for 30 min at 90 °C in a temperature controlled water bath. A visual color change in the
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br Glioblastoma Enhanced radiation sensitization
2020-08-07
Glioblastoma Enhanced radiation sensitization Hydroxychloroquine Lysosomal pH Melanoma Enhanced antitumor effect Bafilomycin A1 Vacuolar-ATPase Nasopharyngeal carcinoma Enhanced antitumor effect cells Gastric cancer cells Osteosarcoma cells Colon cancer cells Spautin-1 Inhib
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br Fig presents an exemplary image
2020-08-07
Fig. 2 presents an exemplary image of the enlarged nucleus, along with the stroma overlapping certain parts of the cell. The original registered image is presented on the left. The middle one illustrates the cell nucleus with an overlapping stroma area, marked in orange. The right-hand image is th
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br Androgen receptor is a nuclear receptor transcriptional
2020-08-06
Androgen receptor is a nuclear receptor/transcriptional factor with transcriptional activity that depends on the transactivation domains: AF-1 and AF-2 domains, as well as LBD domains. The basic transcrip-tional machinery consists of the following processes: first, androgen receptor signaling is a
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br Olfat G Shaker Mahmoud A Senousy br Supplemental
2020-08-06
Olfat G. Shaker, Mahmoud A. Senousy Supplemental Table 2 Hardy-Weinberg Equilibrium for 6 SNPs in Patients With BC and in Control Subjects SNP No. Observed Frequencies Expected Frequencies P TC CC TT TC CC GC CC GG GC CC TC CC TT TC CC CG
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br Four potentially functional variants of TGFB and HSPB gen
2020-08-06
Four potentially functional variants of TGFB1 and HSPB1 genes were selected from the gene SNP database of the National Institute of Environmental Health Sciences Genome Program and related lit-erature using the LD TAG SNP Selection tool (https://snpinfo.niehs. nih.gov/snpinfo/snptag.html). The sel
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br Results br Patient Characteristics and
2020-08-06
Results Patient Characteristics and Irinotecan-Based Chemotherapy In total, 102 patients were included in this study (Supplementary material 2). The patient characteristics are described in Table 1. According to the inclusion criteria, all patients had undergone resection of the primary tumo
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Austin PC Optimal caliper widths for propensity
2020-08-06
20. Austin PC. Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharma Stat. 2011;10:150–161. 22. Tosoian JJ, Mamawala M, Epstein JI, et al. Intermediate and longer-term outcomes from a prospective a