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br Conflict of interest br The authors declare
2020-07-04
Conflict of interest The authors declare no potential conflicts of interest. Funding Appendix A. Supplementary data References Farnsworth, W.E., 1973. Human prostatic dehydroepiandrosterone sulfate sulfatase. Klein, H., Bressel, M., Kastendieck, H., Voigt, K.D., 1988a. Quantitati
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br Our findings regarding the
2020-03-24
Our findings regarding the associations of the baseline BMI, WC, and WHR with pancreatic cancer risk are also in agreement with the results of previous cohort studies [4e7]. However, we found little evidence of an association with BMI earlier in life, in contrast to the results of several previous
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Pluda JM Tumor associated angiogenesis mechanisms clinical i
2020-03-24
[45] Pluda JM. Tumor-associated angiogenesis: mechanisms, clinical implications, and therapeutic strategies. Semin Oncol 1997;24(2):203e18. Cellular Signalling 62 (2019) 109350 Contents lists available at ScienceDirect Cellular Signalling journal homepage: www.elsevier.com/locate/cellsig
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br altered in the kidneys
2020-03-24
altered in the kidneys of mice with either individual ADD3 knockout or a dual loss of ADD2 and ADD3 [51]. Hence, it is reasonable to suggest that ADD1 in addition to canonical heterooligomerization with ADD3 or ADD2, is capable of forming homooligomers and functioning in-dependently from other
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br characteristics male sex lower eGFR at diagnosis below
2020-03-24
characteristics: male sex, lower eGFR at diagnosis (below 60 mL/minute/1.73 m2), chemotherapeutic agents administered (especially cyclophosphamide), and nephrec-tomy performed. In the multivariable analysis, the statistically significant risk factors of renal impairment were male sex, lower eGF
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br Please cite this article as Mei D et al
2020-03-24
Please cite this article as: Mei D et al., Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer, Acta Pharmaceutica Sinica B, https://doi.org/10.1016/j.apsb.2019.03.006 + MODEL Priming autophagic cell
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br for preventing endometrial cancer and improve progestin b
2020-03-24
for preventing endometrial cancer and improve progestin-based con-servative treatment in early stage endometrial cancer. Authors’ contributions The conception and design of the study: Xiaojun Chen and Congjian The acquisition of data: Qiaoying Lv, Liying Xie, Yali Cheng, Weiwei Shan, Chen
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br AGGTTGACGAACCGCTCATTC br CONTACT FOR REAGENT
2020-03-17
AGGTTGACGAACCGCTCATTC CONTACT FOR REAGENT AND RESOURCE SHARING Further information and requests for resources and reagents should be directed to and will fulfilled by the Lead Contact, Feixiong Cheng ([email protected]). EXPERIMENTAL MODEL AND SUBJECT DETAILS Cell Lines Human breast ca
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br Conclusion br In summary this study demonstrates that
2019-11-11
Conclusion In summary, this Dorsomorphin study demonstrates that patients with thy-roid cancer have a clear need for a strong patient-surgeon relationship, characterized by informational and emotional support as well as respect for the individual. When these needs were met, patients experienced
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br zdelikara A Tan M
2019-11-11
16. Özdelikara A, Tan M. The effect of reflexology on the quality of life with breast cancer patients. Complement Ther Clin Pract 2017; 29:122-9. 17. Flynn LL, Bush TR, Sikorskii A, Mukherjee R, Wyatt G. Understanding the role of stimulation in reflexology: development and testing of a robotic
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br The outline of the paper
2019-11-11
The outline of the paper is as follows. In Section 2, we give a brief overview of the modeling of the cancer L-NAME hydrochloride invasion into the extracellular matrix. In Section 3, we describe the adaptive moving mesh finite difference method. Section 4 provides the numerical details of the ad
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br Recent reports propose that the natural
2019-10-24
Recent reports propose that the natural polysaccharide-based ma-terials advance the innovative approaches in drug delivery, therapeutic strategies and tissue engineering. The sulfated polysaccharides such as fucoidan, carrageenan, alginate, and chitosan have preferable phar-macological properties
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br Isothermal titration calorimetry ITC A nity constants and
2019-10-16
Isothermal titration calorimetry (ITC). Affinity constants and binding stoichiometry between native/conjugate proteins and mAbs were determined by isothermal titration calorimetry using a VP-ITC MicroCalorimeter (GE Healthcare, Uppsala, Sweden) provided with a ThermoVac accessory for thermostatting
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Trichostatin A (TSA) br Patients screened br Patients enroll
2019-10-15
Patients screened Patients enrolled Patients received at least 1 dose of medication Patients completed study Patients not enrolled (n=50) Patients withdrawn (n=12) Patient whished to leave the study (n=3) Investigator’s decision (n=3) Major protocol violation (n=2) Pa
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br average diameter of nm Fe
2019-10-14
average diameter of 10 nm. [email protected] nanoparticles were fabricated by reverse-phase microemulsion method. It is clearly that the core-shell structure nanoparticles consist of SiO2 layer with thickness of about 10 nm, as shown in Fig. 1c. Finally, the amino-modified [email protected] nanoparticles rea