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br Model evaluation criteria br In
2019-10-09
2.2. Model evaluation criteria In medical diagnosis, an outcome of a test is called negative if a person is not detected with the disease (esophageal cancer here). In the data-set, a person diagnosed with esophageal cancer is described as ‘abnormal’, ‘normal’ otherwise. Hence, we use ‘abnormal’
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br Pathway analysis of the ESA miRNAs and their performance
2019-10-08
3.2. Pathway analysis of the ESA miRNAs and their performance on classification The top-ranked miRNAs and mRNAs by the estimated essential score alterations (ESA) were kept for the following analysis. Differential Jasplakinolide analysis was carried out by using the edgeR package [23] in R for
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br Giorgio Corti et al br version Instead
2019-10-07
Giorgio Corti et al version). Instead, the FUSION panel has been designed selecting the most frequent oncogenic kinases involved in fusions and the most frequently rearranged partners, identified on the basis of the available literature and The Cancer Genome Atlas database. Custom probes wer
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br Table br STOP CRC intervention activities
2019-10-01
Table 1 STOP CRC intervention activities. Data organization and management Updating claims data (e.g., historical colonoscopies) Initial EHR training Testing EHR tools Training of additional staff (e.g., MA) Execution of lab interface agreements Lab Fulvestrant (ICI 182,780) t
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br Provenance and peer review
2019-10-01
Provenance and peer review This article has undergone peer review. Research data (data sharing and collaboration) There are no linked research data sets for this paper. All available data can be obtained by contacting the corresponding author. References C. Argudo, M. Fernández-Abel
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br Figure A Heterozygous P R
2019-09-24
Figure 2. A Heterozygous P179R Mutation in PP2A-Aa Decreases PP2AB56 Assembly and Targeting (A) Schematic of PPP2R1A gene-targeting strategy. Exons, rectangles; loxP sites, triangles; ITR, AAV-speciÞc inverted tandem repeats; homologous sequences, green and red dashed lines. (B) Sanger seque
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b iframe width height src https www youtube com
2019-09-23
r> Because all responses occurred in the HR-deficient subset, we assessed whether HRD score correlated with percent change of tumor area from baseline in this subset of patients. No correlation was ob-served (Fig. 4A, Spearman r = 0.050; p = 0.87). Thus, while a positive HRD test enriched for respo
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br Contents lists available at ScienceDirect br
2019-09-16
Contents lists available at ScienceDirect Acta Biomaterialia Full length article 3D printing of hydrogel scaffolds for future application in photothermal therapy of breast cancer and tissue repair Yongxiang Luo ⇑, Xiaoyue Wei, Yilin Wan, Xin Lin, Zhiyong Wang, Peng Huang ⇑ Marshall La
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Biomaterials br spectroscopy and porosity analysis
2019-09-16
Biomaterials 217 (2019) 119311 spectroscopy, and porosity analysis. PCa was selected as a model cancer as it metastasizes to bone and the CA scaffolds resemble the bone mi-croenvironment. PCa cell lines, PC-3, C4-2B and 22Rv1 were selected for culture to provide comparison of 1) functional AR a
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Lung cancer causes irregular cell proliferation in the lung
2019-09-02
Lung cancer causes irregular cell proliferation in the lung through primary genetic or epigenetic modification [9]. Abnormal AMG-176 can form a tumor mass, requiring nutrients and oxygen though blood vessel formation, including angiogenesis [10]. These cells overcome anti-cancer therapy and express
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There are several limitations in this study First the
2019-08-26
There are several limitations in this study. First, the number of cases in which we compared EBUS-TBNA and resected specimens was inadequate due to the fact that most patients who underwent EBUS-TBNA had advanced diseases and thus only a few of them received surgery. Second, the processes of the EBU
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Secondly serum was used to isolate cfDNA rather than plasma
2019-08-26
Secondly, serum was used to isolate cfDNA rather than plasma. Compared to plasma, cfDNA isolated from serum tends to be at a higher concentration because of the extra release of DNA during the coagulation process [32]. cfDNA from serum has superior correlation and concordance rates according to vari
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Recently the KEAP NFE L pathway has been
2019-08-26
Recently, the KEAP1-NFE2L2 pathway has been implicated in the development of EGFR TKI resistance. The KEAP1-NFE2L2 pathway plays a key role in cellular stress response by driving Pifithrin-α (PFTα) of anti-free radical defense genes and detoxification enzymes. When a cell is stressed, key residues
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br Conclusion Several miRNAs have
2019-08-16
Conclusion Several miRNAs have been reported to be deregulated in the body fluids of OSCC patients compared to healthy controls suggesting that these miRNAs can be used as non-invasive biomarkers for oral cancer detection. Several Sevoflurane cohorts have shown different miRNA signatures, perhap
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There are several guidelines that provide circumstances
2019-08-16
There are several guidelines that provide circumstances in which screening is appropriate in younger populations [[1], [2], [3]]. Currently there is inadequate evidence to determine that more intensive screening for higher risk populations produces any long term benefit. While the evidence in this C